KMID : 0878220090210030209
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Journal of Sasang Constitutional Medicine 2009 Volume.21 No. 3 p.209 ~ p.215
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A Clinical Case of Liver Injury with Administration ofYeoldahanso-tang plus Rheum rhabarbarum
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Kwon Eun-Mi
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Abstract
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1.Objects: This case study reports a liver injury in treatment of constipation with Yeoldahanso-tang plus Rheum rhabarbarum.
2.Methods: The patient¡¯s subjective symptoms and the laboratory data including aspartate transaminase(AST), alanine transaminase(ALT), alkaline phosphatase(ALP), and gamma(¥ã)-glutamyl transpeptidase(GGT) were observed before and after liver injury. We used the Roussel Uclaf Causality Assessment Method(RUCAM) scale in order to find out whether if Yeoldahanso-tang plus Rheum rhabarbarum was related with the liver injury.
3.Results: The patient¡¯s AST and ALT were elevated more than twice after a 3week administration period of herbal medicine. After discontinuation of the herbal medicine and administration of hepatic protective medication, AST and ALT decreased. The patient¡¯s general condition improved during hospitalization. The RUCAM score was estimated at 8.
4.Conclusions: This case is presented to bring more attention to the toxicity of herbal medicine.
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KEYWORD
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Herbal medicine, Liver Injury, Yeoldahanso-tang, Rheum rhabarbarum
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